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Rev. chil. infectol ; 27(5): 437-448, oct. 2010. ilus
Article in Spanish | LILACS | ID: lil-572011

ABSTRACT

De los 25 anti-retrovirales disponibles en el mercado, sólo 16 están autorizados en la edad pediátrica. Los antiretrovirales, pertenecientes a las tres primeras familias, usados desde hace dos décadas, continúan vigentes y son parte importante de la terapia anti-retroviral en niños naïve. Se describen las dosis, presentaciones y asociaciones actuales de estos fármacos en la edad pediátrica y además se comentan las nuevas co-formulaciones que permitirán disminuir el número de dosis, mejorar la tolerancia y por lo tanto conseguir mejor adherencia de los pacientes pediátricos.


Of the 25 antiretroviral drugs available in the market, only 16 are allowed for prescription in the pediatric patients. The antiretroviral, pertaining to the first three families, used for two decades, remain valid and are important components of antiretroviral therapy in naive children. We describe doses, presentations and current associations for these drugs in children, and also discuss new co-formulations that will reduce the number of doses, improve tolerance and therefore achieve better adherence of pediatric patients.


Subject(s)
Child , Humans , Anti-Retroviral Agents/administration & dosage , HIV Infections/drug therapy , Acquired Immunodeficiency Syndrome/drug therapy , Anti-HIV Agents/administration & dosage , Drug Administration Schedule , HIV Protease Inhibitors/administration & dosage , HIV Reverse Transcriptase/antagonists & inhibitors , Reverse Transcriptase Inhibitors/administration & dosage
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